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Targeting Lysosomes to Reverse Hydroquinone-Induced Autophagy Defects and Oxidative Damage in Human Retinal Pigment Epithelial Cells
In age-related macular degeneration (AMD), hydroquinone (HQ)-induced oxidative damage in retinal pigment epithelium (RPE) is believed to be an early event contributing to dysregulation of inflammatory cytokines and vascular endothelial growth factor (VEGF) homeostasis. However, the roles of antioxid...
Autores principales: | Abokyi, Samuel, Shan, Sze-Wan, Lam, Christie Hang-I, Catral, Kirk Patrick, Pan, Feng, Chan, Henry Ho-Lung, To, Chi-Ho, Tse, Dennis Yan-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396439/ https://www.ncbi.nlm.nih.gov/pubmed/34445748 http://dx.doi.org/10.3390/ijms22169042 |
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