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Effects on Metabolism in Astrocytes Caused by cGAMP, Which Imitates the Initial Stage of Brain Metastasis

The second messenger 2′3′-cyclic-GMP-AMP (cGAMP) is thought to be transmitted from brain carcinomas to astrocytes via gap junctions, which functions to promote metastasis in the brain parenchyma. In the current study, we established a method to introduce cGAMP into astrocytes, which simulates the st...

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Detalles Bibliográficos
Autores principales: Okawa, Toya, Hara, Kurumi, Goto, Momoko, Kikuchi, Moe, Kogane, Masataka, Hatakeyama, Hiroto, Tanaka, Hiroki, Shirane, Daiki, Akita, Hidetaka, Hisaka, Akihiro, Sato, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396466/
https://www.ncbi.nlm.nih.gov/pubmed/34445736
http://dx.doi.org/10.3390/ijms22169028