Cargando…

Nitro-Oleic Acid (NO(2)-OA) Improves Systolic Function in Dilated Cardiomyopathy by Attenuating Myocardial Fibrosis

Nitro-oleic acid (NO(2)-OA), a nitric oxide (NO)- and nitrite (NO(2)(−))-derived electrophilic fatty acid metabolite, displays anti-inflammatory and anti-fibrotic signaling actions and therapeutic benefit in murine models of ischemia-reperfusion, atrial fibrillation, and pulmonary hypertension. Musc...

Descripción completa

Detalles Bibliográficos
Autores principales: Braumann, Simon, Schumacher, Wibke, Im, Nam Gyu, Nettersheim, Felix Sebastian, Mehrkens, Dennis, Bokredenghel, Senai, Hof, Alexander, Nies, Richard Julius, Adler, Christoph, Winkels, Holger, Knöll, Ralph, Freeman, Bruce A., Rudolph, Volker, Klinke, Anna, Adam, Matti, Baldus, Stephan, Mollenhauer, Martin, Geißen, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396484/
https://www.ncbi.nlm.nih.gov/pubmed/34445757
http://dx.doi.org/10.3390/ijms22169052