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Nitro-Oleic Acid (NO(2)-OA) Improves Systolic Function in Dilated Cardiomyopathy by Attenuating Myocardial Fibrosis
Nitro-oleic acid (NO(2)-OA), a nitric oxide (NO)- and nitrite (NO(2)(−))-derived electrophilic fatty acid metabolite, displays anti-inflammatory and anti-fibrotic signaling actions and therapeutic benefit in murine models of ischemia-reperfusion, atrial fibrillation, and pulmonary hypertension. Musc...
Autores principales: | Braumann, Simon, Schumacher, Wibke, Im, Nam Gyu, Nettersheim, Felix Sebastian, Mehrkens, Dennis, Bokredenghel, Senai, Hof, Alexander, Nies, Richard Julius, Adler, Christoph, Winkels, Holger, Knöll, Ralph, Freeman, Bruce A., Rudolph, Volker, Klinke, Anna, Adam, Matti, Baldus, Stephan, Mollenhauer, Martin, Geißen, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396484/ https://www.ncbi.nlm.nih.gov/pubmed/34445757 http://dx.doi.org/10.3390/ijms22169052 |
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