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Cytostatic Effect of a Novel Mitochondria-Targeted Pyrroline Nitroxide in Human Breast Cancer Lines

Mitochondria have emerged as a prospective target to overcome drug resistance that limits triple-negative breast cancer therapy. A novel mitochondria-targeted compound, HO-5114, demonstrated higher cytotoxicity against human breast cancer lines than its component-derivative, Mito-CP. In this study,...

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Detalles Bibliográficos
Autores principales: Andreidesz, Kitti, Szabo, Aliz, Kovacs, Dominika, Koszegi, Balazs, Bagone Vantus, Viola, Vamos, Eszter, Isbera, Mostafa, Kalai, Tamas, Bognar, Zita, Kovacs, Krisztina, Gallyas, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396499/
https://www.ncbi.nlm.nih.gov/pubmed/34445722
http://dx.doi.org/10.3390/ijms22169016