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Paradoxical Pro-angiogenic Effect of Low-Dose Ellipticine Identified by In Silico Drug Repurposing

Inadequate vessel maintenance or growth causes ischemia in diseases such as myocardial infarction, stroke, and neurodegenerative disorders. Therefore, developing an effective strategy to salvage ischemic tissues using a novel compound is urgent. Drug repurposing has become a widely used method that...

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Detalles Bibliográficos
Autores principales: Oh, Jisu, Lee, Hyeon Hae, Jeong, Yunhui, Yoon, Siyeong, An, Hyun-Ju, Baek, Minjung, Kim, Do Kyung, Lee, Soonchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396501/
https://www.ncbi.nlm.nih.gov/pubmed/34445773
http://dx.doi.org/10.3390/ijms22169067