Cargando…

Paradoxical Pro-angiogenic Effect of Low-Dose Ellipticine Identified by In Silico Drug Repurposing

Inadequate vessel maintenance or growth causes ischemia in diseases such as myocardial infarction, stroke, and neurodegenerative disorders. Therefore, developing an effective strategy to salvage ischemic tissues using a novel compound is urgent. Drug repurposing has become a widely used method that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oh, Jisu, Lee, Hyeon Hae, Jeong, Yunhui, Yoon, Siyeong, An, Hyun-Ju, Baek, Minjung, Kim, Do Kyung, Lee, Soonchul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396501/ https://www.ncbi.nlm.nih.gov/pubmed/34445773 http://dx.doi.org/10.3390/ijms22169067

Ejemplares similares

Pro-Angiogenic and Osteogenic Effects of Adipose Tissue-Derived Pericytes Synergistically Enhanced by Nel-like Protein-1
por: An, Hyun-Ju, et al.
Publicado: (2021)

Sustained Exposure of Substance P Causes Tendinopathy
por: Oh, Seo Yoon, et al.
Publicado: (2020)

Repurposing Ellipticine Hydrochloride to Combat Colistin-Resistant Extraintestinal Pathogenic E. coli (ExPEC)
por: Lu, Hao, et al.
Publicado: (2020)

Incidence and Survival Rates of Cutaneous Melanoma in South Korea Using Nationwide Health Insurance Claims Data
por: Kim, TaeHo, et al.
Publicado: (2022)

Serious Clinical Outcomes of COVID-19 Related to Acetaminophen or NSAIDs from a Nationwide Population-Based Cohort Study
por: Kim, Jin-Woo, et al.
Publicado: (2023)

Comparison of whole trunk muscle mass between healthy and lumbar herniated nucleus pulposus patients using abdominal pelvic computed tomography
por: Oh, Chi-Hoon, et al.
Publicado: (2023)

Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid
por: Lee, Bo-Eun, et al.
Publicado: (2021)

Pharmacokinetics of Peptide Mediated Delivery of Anticancer Drug Ellipticine
por: Ma, Weina, et al.
Publicado: (2012)

The Effect of the COVID-19 Pandemic on Early Adolescent Fractures in the Republic of Korea
por: Park, HyunSeo, et al.
Publicado: (2023)

Ellipticine cytotoxicity to cancer cell lines — a comparative study
por: Stiborová, Marie, et al.
Publicado: (2011)

Synthesis and Evaluation of Novel Ellipticines and Derivatives as Inhibitors of Phytophthora infestans
por: McKee, Mary L., et al.
Publicado: (2020)

Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study
por: Lee, Younghun, et al.
Publicado: (2021)

Effect of Dosing Interval on Compliance of Osteoporosis Patients on Bisphosphonate Therapy: Observational Study Using Nationwide Insurance Claims Data
por: Lee, Hyunil, et al.
Publicado: (2021)

Aspirin Is Related to Worse Clinical Outcomes of COVID-19
por: Kim, Isaac, et al.
Publicado: (2021)

The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells
por: Poljaková, Jitka, et al.
Publicado: (2008)

Anticancer and Immunomodulatory Activities of a Novel Water-Soluble Derivative of Ellipticine
por: Costa de Oliveira, Regiane, et al.
Publicado: (2020)

Genome-Wide Association Study Identifies Genetic Variants Associated with Rotator Cuff Tear—A Pilot Study
por: An, Hyun-Ju, et al.
Publicado: (2022)

Reliability of the TT-TG Index Versus TT-TG Distance on MRI: Morphometric Analyses in Asian Children and Adolescents
por: Park, Sin Hyung, et al.
Publicado: (2023)

ATM participates in the regulation of viability and cell cycle via ellipticine in bladder cancer
por: Tao, Shuixiang, et al.
Publicado: (2017)

Modeling the Antileukemia Activity of Ellipticine-Related Compounds: QSAR and Molecular Docking Study
por: Márquez, Edgar, et al.
Publicado: (2019)

Epidemiology of pediatric fractures before versus during the coronavirus disease 2019 pandemic
por: Oh, Chi Hoon, et al.
Publicado: (2022)

The Association of Low Skeletal Muscle Mass with Complex Distal Radius Fracture
por: Oh, Chi-Hoon, et al.
Publicado: (2022)

Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo
por: Wu, Yan, et al.
Publicado: (2012)

Formation of DNA Adducts by Ellipticine and Its Micellar Form in Rats — A Comparative Study
por: Stiborova, Marie, et al.
Publicado: (2014)

Sequence Effect of Self-Assembling Peptides on the Complexation and In Vitro Delivery of the Hydrophobic Anticancer Drug Ellipticine
por: Fung, Shan Yu, et al.
Publicado: (2008)

Novel 11-Substituted Ellipticines as Potent Anticancer Agents with Divergent Activity against Cancer Cells
por: Miller, Charlotte M., et al.
Publicado: (2019)

The expression of substance P and calcitonin gene-related peptide is associated with the severity of tendon degeneration in lateral epicondylitis
por: Han, Soo-Hong, et al.
Publicado: (2021)

Pro-angiogenic therapeutics for preeclampsia
por: Eddy, Adrian C., et al.
Publicado: (2018)

Bone marrow stem cells incubated with ellipticine regenerate articular cartilage by attenuating inflammation and cartilage degradation in rabbit model
por: Hossain, Mohammad Amjad, et al.
Publicado: (2023)

Demonstration of a potent RET transcriptional inhibitor for the treatment of medullary thyroid carcinoma based on an ellipticine derivative
por: Kumarasamy, Vishnu Muthuraj, et al.
Publicado: (2017)

Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol
por: Lee, Szu, et al.
Publicado: (2023)

GDF-11 as a Potential Cardiac Pro-Angiogenic Factor
por: Kato, Tomohiro, et al.
Publicado: (2023)

Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani
por: Hassan, Ahmed H. E., et al.
Publicado: (2023)

In silico repurposing of antipsychotic drugs for Alzheimer’s disease
por: Kumar, Shivani, et al.
Publicado: (2017)

In Silico Repurposed Drugs against Monkeypox Virus
por: Lam, Hilbert Yuen In, et al.
Publicado: (2022)

Arterial Hypertension Is Characterized by Imbalance of Pro-Angiogenic versus Anti-Angiogenic Factors
por: Marek-Trzonkowska, Natalia, et al.
Publicado: (2015)

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells
por: Cerna, Tereza, et al.
Publicado: (2018)

Pro-Angiogenic Effects of Chalcone Derivatives in Zebrafish Embryos in Vivo
por: Chen, Yau-Hung, et al.
Publicado: (2015)

Control of the Immune Response by Pro-Angiogenic Factors
por: Voron, Thibault, et al.
Publicado: (2014)

Leptin’s Pro-Angiogenic Signature in Breast Cancer
por: Gonzalez-Perez, Ruben Rene, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_aokdmrlu3kjr5bef4p7ravn1tc