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GPCR Partners as Cancer Driver Genes: Association with PH-Signal Proteins in a Distinctive Signaling Network

The essential role of G-protein coupled receptors (GPCRs) in tumor growth is recognized, yet a GPCR based drug in cancer is rare. Understanding the molecular path of a tumor driver gene may lead to the design and development of an effective drug. For example, in members of protease-activated recepto...

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Detalles Bibliográficos
Autores principales: Nag, Jeetendra Kumar, Malka, Hodaya, Appasamy, Priyanga, Sedley, Shoshana, Bar-Shavit, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396503/
https://www.ncbi.nlm.nih.gov/pubmed/34445691
http://dx.doi.org/10.3390/ijms22168985