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TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity

The cytoplasmic retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs) initiate interferon (IFN) production and antiviral gene expression in response to RNA virus infection. Consequently, RLR signalling is tightly regulated by both host and viral factors. Tripartite motif protein 25 (TRIM25) i...

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Detalles Bibliográficos
Autores principales: Atkinson, Sarah C., Heaton, Steven M., Audsley, Michelle D., Kleifeld, Oded, Borg, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396550/
https://www.ncbi.nlm.nih.gov/pubmed/34445801
http://dx.doi.org/10.3390/ijms22169094