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The Proteasome Inhibitor Bortezomib Induces Apoptosis and Activation in Gel-Filtered Human Platelets

Bortezomib (BTZ) has demonstrated its efficacy in several hematological disorders and has been associated with thrombocytopenia. There is controversy about the effect of BTZ on human platelets, so we set out to determine its effect on various types of platelet samples. Human platelets were investiga...

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Detalles Bibliográficos
Autores principales: Ghansah, Harriet, Debreceni, Ildikó Beke, Fejes, Zsolt, Nagy, Béla, Kappelmayer, János
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396574/
https://www.ncbi.nlm.nih.gov/pubmed/34445660
http://dx.doi.org/10.3390/ijms22168955