Molecular Mechanisms of Skewed X-Chromosome Inactivation in Female Hemophilia Patients—Lessons from Wide Genome Analyses

Introduction: Hemophilia A (HA) is an X-linked bleeding disorder caused by factor VIII (FVIII) deficiency or dysfunction due to F8 gene mutations. HA carriers are usually asymptomatic because their FVIII levels correspond to approximately half of the concentration found in healthy individuals. Howev...

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Detalles Bibliográficos
Autores principales: Dardik, Rima, Avishai, Einat, Lalezari, Shadan, Barg, Assaf A., Levy-Mendelovich, Sarina, Budnik, Ivan, Barel, Ortal, Khavkin, Yulia, Kenet, Gili, Livnat, Tami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396640/
https://www.ncbi.nlm.nih.gov/pubmed/34445777
http://dx.doi.org/10.3390/ijms22169074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396640/
https://www.ncbi.nlm.nih.gov/pubmed/34445777
http://dx.doi.org/10.3390/ijms22169074

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