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Natural Mutations Affect Structure and Function of gC1q Domain of Otolin-1

Otolin-1 is a scaffold protein of otoliths and otoconia, calcium carbonate biominerals from the inner ear. It contains a gC1q domain responsible for trimerization and binding of Ca(2+). Knowledge of a structure–function relationship of gC1q domain of otolin-1 is crucial for understanding the biology...

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Detalles Bibliográficos
Autores principales: Hołubowicz, Rafał, Ożyhar, Andrzej, Dobryszycki, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396674/
https://www.ncbi.nlm.nih.gov/pubmed/34445792
http://dx.doi.org/10.3390/ijms22169085