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Natural Mutations Affect Structure and Function of gC1q Domain of Otolin-1
Otolin-1 is a scaffold protein of otoliths and otoconia, calcium carbonate biominerals from the inner ear. It contains a gC1q domain responsible for trimerization and binding of Ca(2+). Knowledge of a structure–function relationship of gC1q domain of otolin-1 is crucial for understanding the biology...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396674/ https://www.ncbi.nlm.nih.gov/pubmed/34445792 http://dx.doi.org/10.3390/ijms22169085 |