Acid Sphingomyelinase, a Lysosomal and Secretory Phospholipase C, Is Key for Cellular Phospholipid Catabolism

Here, we present the main features of human acid sphingomyelinase (ASM), its biosynthesis, processing and intracellular trafficking, its structure, its broad substrate specificity, and the proposed mode of action at the surface of the phospholipid substrate carrying intraendolysosomal luminal vesicl...

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Detalles Bibliográficos
Autores principales: Breiden, Bernadette, Sandhoff, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396676/
https://www.ncbi.nlm.nih.gov/pubmed/34445706
http://dx.doi.org/10.3390/ijms22169001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396676/
https://www.ncbi.nlm.nih.gov/pubmed/34445706
http://dx.doi.org/10.3390/ijms22169001

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