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The evolutionary history of topological variations in the CPA/AT transporters

CPA/AT transporters are made up of scaffold and a core domain. The core domain contains two non-canonical helices (broken or reentrant) that mediate the transport of ions, amino acids or other charged compounds. During evolution, these transporters have undergone substantial changes in structure, to...

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Detalles Bibliográficos
Autores principales: Sudha, Govindarajan, Bassot, Claudio, Lamb, John, Shu, Nanjiang, Huang, Yan, Elofsson, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396727/
https://www.ncbi.nlm.nih.gov/pubmed/34403419
http://dx.doi.org/10.1371/journal.pcbi.1009278