Safety verification for polysorbate 20, pharmaceutical excipient for intramuscular administration, in Sprague-Dawley rats and New Zealand White rabbits

Human serum albumin (HSA) has been widely used as a pharmaceutical excipient in Botulinum toxin serotype A (BoNT/A) products that are indicated for use in therapeutics and cosmetics. However, HSA as a human-derived material has some concerns, such as the potential risk of transmission of infectious...

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Detalles Bibliográficos
Autores principales: Kim, Junhyung, Kwak, Seongsung, Park, Mi-Sun, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Lee, Jangmi, Son, Woo-Chan, Kang, Won-ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396741/
https://www.ncbi.nlm.nih.gov/pubmed/34449810
http://dx.doi.org/10.1371/journal.pone.0256869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396741/
https://www.ncbi.nlm.nih.gov/pubmed/34449810
http://dx.doi.org/10.1371/journal.pone.0256869

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