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Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome

Our laboratory has demonstrated that captopril, an angiotensin converting enzyme inhibitor, mitigates hematopoietic injury following total body irradiation in mice. Improved survival in mice is correlated with improved recovery of mature blood cells and bone marrow, reduction of radiation-induced in...

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Detalles Bibliográficos
Autores principales: Rittase, W. Bradley, McCart, Elizabeth A., Muir, Jeannie M., Bouten, Roxane M., Slaven, John E., Mungunsukh, Ognoon, Bylicky, Michelle A., Wilkins, W. Louis, Lee, Sang-Ho, Gudmundsson, Kristbjorn O., Di Pucchio, Tiziana, Olsen, Cara H., Du, Yang, Day, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396780/
https://www.ncbi.nlm.nih.gov/pubmed/34449797
http://dx.doi.org/10.1371/journal.pone.0256208