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Neurovascular imaging with QUTE-CE MRI in APOE4 rats reveals early vascular abnormalities

Cerebrovascular abnormality is linked to Alzheimer’s disease and related dementias (ADRDs). ApoE-Ɛ4 (APOE4) is known to play a critical role in neurovascular dysfunction, however current medical imaging technologies are limited in quantification. This cross-sectional study tested the feasibility of...

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Detalles Bibliográficos
Autores principales: Leaston, Joshua, Ferris, Craig F., Kulkarni, Praveen, Chandramohan, Dharshan, van de Ven, Anne L., Qiao, Ju, Timms, Liam, Sepulcre, Jorge, El Fakhri, Georges, Ma, Chao, Normandin, Marc D., Gharagouzloo, Codi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396782/
https://www.ncbi.nlm.nih.gov/pubmed/34449808
http://dx.doi.org/10.1371/journal.pone.0256749