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Aberrantly Glycosylated IgA1 in IgA Nephropathy: What We Know and What We Don’t Know

IgA nephropathy (IgAN), the most common primary glomerular disease worldwide, is characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 hinge region (HR) has up to six clustered O-glycans consisting of Ser/Thr-linked N-acetylgalactosamine usually with β1,3-linked galact...

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Detalles Bibliográficos
Autores principales: Ohyama, Yukako, Renfrow, Matthew B., Novak, Jan, Takahashi, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396900/
https://www.ncbi.nlm.nih.gov/pubmed/34441764
http://dx.doi.org/10.3390/jcm10163467