Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus
Bariatric surgery is an emerging therapeutic approach for obese type 2 diabetes mellitus (T2DM) patients, with proven benefits for achieving target glucose control and even remission of diabetes. However, the effect of bariatric surgery upon diabetic retinopathy is still a subject of debate as some...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396947/ https://www.ncbi.nlm.nih.gov/pubmed/34442032 http://dx.doi.org/10.3390/jcm10163736 |
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author | Dascalu, Ana Maria Stoian, Anca Pantea Cherecheanu, Alina Popa Serban, Dragos Costea, Daniel Ovidiu Tudosie, Mihail Silviu Stana, Daniela Tanasescu, Denisa Sabau, Alexandru Dan Gangura, Gabriel Andrei Costea, Andreea Cristina Nicolae, Vanessa Andrada Smarandache, Catalin Gabriel |
author_facet | Dascalu, Ana Maria Stoian, Anca Pantea Cherecheanu, Alina Popa Serban, Dragos Costea, Daniel Ovidiu Tudosie, Mihail Silviu Stana, Daniela Tanasescu, Denisa Sabau, Alexandru Dan Gangura, Gabriel Andrei Costea, Andreea Cristina Nicolae, Vanessa Andrada Smarandache, Catalin Gabriel |
author_sort | Dascalu, Ana Maria |
collection | PubMed |
description | Bariatric surgery is an emerging therapeutic approach for obese type 2 diabetes mellitus (T2DM) patients, with proven benefits for achieving target glucose control and even remission of diabetes. However, the effect of bariatric surgery upon diabetic retinopathy is still a subject of debate as some studies show a positive effect while others raise concerns about potential early worsening effects. We performed a systematic review, on PubMed, Science Direct, and Web of Science databases regarding the onset and progression of diabetic retinopathy in obese T2DM patients who underwent weight-loss surgical procedures. A total of 6375 T2DM patients were analyzed. Most cases remained stable after bariatric surgery (89.6%). New onset of diabetic retinopathy (DR) was documented in 290 out of 5972 patients (4.8%). In cases with DR at baseline, progression was documented in 50 out of 403 (12.4%) and regression in 90 (22.3%). Preoperative careful preparation of hemoglobin A1c (HbA1c), blood pressure, and lipidemia should be provided to minimize the expectation of DR worsening. Ophthalmologic follow-up should be continued regularly in the postoperative period even in the case of diabetic remission. Further randomized trials are needed to better understand the organ-specific risk factors for progression and provide personalized counseling for T2DM patients planned for bariatric surgery. |
format | Online Article Text |
id | pubmed-8396947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83969472021-08-28 Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus Dascalu, Ana Maria Stoian, Anca Pantea Cherecheanu, Alina Popa Serban, Dragos Costea, Daniel Ovidiu Tudosie, Mihail Silviu Stana, Daniela Tanasescu, Denisa Sabau, Alexandru Dan Gangura, Gabriel Andrei Costea, Andreea Cristina Nicolae, Vanessa Andrada Smarandache, Catalin Gabriel J Clin Med Review Bariatric surgery is an emerging therapeutic approach for obese type 2 diabetes mellitus (T2DM) patients, with proven benefits for achieving target glucose control and even remission of diabetes. However, the effect of bariatric surgery upon diabetic retinopathy is still a subject of debate as some studies show a positive effect while others raise concerns about potential early worsening effects. We performed a systematic review, on PubMed, Science Direct, and Web of Science databases regarding the onset and progression of diabetic retinopathy in obese T2DM patients who underwent weight-loss surgical procedures. A total of 6375 T2DM patients were analyzed. Most cases remained stable after bariatric surgery (89.6%). New onset of diabetic retinopathy (DR) was documented in 290 out of 5972 patients (4.8%). In cases with DR at baseline, progression was documented in 50 out of 403 (12.4%) and regression in 90 (22.3%). Preoperative careful preparation of hemoglobin A1c (HbA1c), blood pressure, and lipidemia should be provided to minimize the expectation of DR worsening. Ophthalmologic follow-up should be continued regularly in the postoperative period even in the case of diabetic remission. Further randomized trials are needed to better understand the organ-specific risk factors for progression and provide personalized counseling for T2DM patients planned for bariatric surgery. MDPI 2021-08-22 /pmc/articles/PMC8396947/ /pubmed/34442032 http://dx.doi.org/10.3390/jcm10163736 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Dascalu, Ana Maria Stoian, Anca Pantea Cherecheanu, Alina Popa Serban, Dragos Costea, Daniel Ovidiu Tudosie, Mihail Silviu Stana, Daniela Tanasescu, Denisa Sabau, Alexandru Dan Gangura, Gabriel Andrei Costea, Andreea Cristina Nicolae, Vanessa Andrada Smarandache, Catalin Gabriel Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus |
title | Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus |
title_full | Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus |
title_fullStr | Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus |
title_full_unstemmed | Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus |
title_short | Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus |
title_sort | outcomes of diabetic retinopathy post-bariatric surgery in patients with type 2 diabetes mellitus |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396947/ https://www.ncbi.nlm.nih.gov/pubmed/34442032 http://dx.doi.org/10.3390/jcm10163736 |
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