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Antibody–Drug Conjugates for the Treatment of Acute Pediatric Leukemia

The clinical development of antibody–drug conjugates (ADCs) has gained momentum in recent years and these agents are gradually moving into frontline regimens for pediatric acute leukemias. ADCs consist of a monoclonal antibody attached to a cytotoxic payload by a cleavable linker. This structure all...

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Detalles Bibliográficos
Autores principales: Stokke, Jamie L., Bhojwani, Deepa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396964/
https://www.ncbi.nlm.nih.gov/pubmed/34441852
http://dx.doi.org/10.3390/jcm10163556