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Morphine-sensitive synaptic transmission emerges in embryonic rat microphysiological model of lower afferent nociceptive signaling

Debilitating chronic pain resulting from genetic predisposition, injury, or acquired neuropathy is becoming increasingly pervasive. Opioid analgesics remain the gold standard for intractable pain, but overprescription of increasingly powerful and addictive opioids has contributed to the current pres...

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Detalles Bibliográficos
Autores principales: Pollard, Kevin J., Bowser, Devon A., Anderson, Wesley A., Meselhe, Mostafa, Moore, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397270/
https://www.ncbi.nlm.nih.gov/pubmed/34452921
http://dx.doi.org/10.1126/sciadv.abj2899