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Morphine-sensitive synaptic transmission emerges in embryonic rat microphysiological model of lower afferent nociceptive signaling
Debilitating chronic pain resulting from genetic predisposition, injury, or acquired neuropathy is becoming increasingly pervasive. Opioid analgesics remain the gold standard for intractable pain, but overprescription of increasingly powerful and addictive opioids has contributed to the current pres...
Autores principales: | Pollard, Kevin J., Bowser, Devon A., Anderson, Wesley A., Meselhe, Mostafa, Moore, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397270/ https://www.ncbi.nlm.nih.gov/pubmed/34452921 http://dx.doi.org/10.1126/sciadv.abj2899 |
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