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On the Metal-Aided Catalytic Mechanism for Phosphodiester Bond Cleavage Performed by Nanozymes

[Image: see text] Recent studies have shown that gold nanoparticles (AuNPs) functionalized with Zn(II) complexes can cleave phosphate esters and nucleic acids. Remarkably, such synthetic nanonucleases appear to catalyze metal (Zn)-aided hydrolytic reactions of nucleic acids similar to metallonucleas...

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Detalles Bibliográficos
Autores principales: Pecina, Adam, Rosa-Gastaldo, Daniele, Riccardi, Laura, Franco-Ulloa, Sebastian, Milan, Emil, Scrimin, Paolo, Mancin, Fabrizio, De Vivo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397296/
https://www.ncbi.nlm.nih.gov/pubmed/34476110
http://dx.doi.org/10.1021/acscatal.1c01215