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Fast Ion-Chelate Dissociation Rate for In Vivo MRI of Labile Zinc with Frequency-Specific Encodability

[Image: see text] Fast ion-chelate dissociation rates and weak ion-chelate affinities are desired kinetic and thermodynamic features for imaging probes to allow reversible binding and to prevent deviation from basal ionic levels. Nevertheless, such properties often result in poor readouts upon ion b...

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Detalles Bibliográficos
Autores principales: Tirukoti, Nishanth D., Avram, Liat, Haris, Talia, Lerner, Benjamin, Diskin-Posner, Yael, Allouche-Arnon, Hyla, Bar-Shir, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397314/
https://www.ncbi.nlm.nih.gov/pubmed/34297566
http://dx.doi.org/10.1021/jacs.1c05376