Substrate Channeling by a Rationally Designed Fusion Protein in a Biocatalytic Cascade

[Image: see text] Substrate channeling, where an intermediate in a multistep reaction is directed toward a reaction center rather than freely diffusing, offers several advantages when employed in catalytic cascades. Here we present a fusion enzyme comprised of an alcohol and aldehyde dehydrogenase,...

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Detalles Bibliográficos
Autores principales: Kummer, Matthew J., Lee, Yoo Seok, Yuan, Mengwei, Alkotaini, Bassam, Zhao, John, Blumenthal, Emmy, Minteer, Shelley D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397353/
https://www.ncbi.nlm.nih.gov/pubmed/34467357
http://dx.doi.org/10.1021/jacsau.1c00180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397353/
https://www.ncbi.nlm.nih.gov/pubmed/34467357
http://dx.doi.org/10.1021/jacsau.1c00180

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