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Substrate Channeling by a Rationally Designed Fusion Protein in a Biocatalytic Cascade
[Image: see text] Substrate channeling, where an intermediate in a multistep reaction is directed toward a reaction center rather than freely diffusing, offers several advantages when employed in catalytic cascades. Here we present a fusion enzyme comprised of an alcohol and aldehyde dehydrogenase,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397353/ https://www.ncbi.nlm.nih.gov/pubmed/34467357 http://dx.doi.org/10.1021/jacsau.1c00180 |