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Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility
Clustering of ligand:receptor complexes on the cell membrane is widely presumed to have functional consequences for subsequent signal transduction. However, it is experimentally challenging to selectively manipulate receptor clustering without altering other biochemical aspects of the cellular syste...
Autores principales: | Chen, Zhongwen, Oh, Dongmyung, Biswas, Kabir Hassan, Zaidel-Bar, Ronen, Groves, Jay T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397371/ https://www.ncbi.nlm.nih.gov/pubmed/34414885 http://dx.doi.org/10.7554/eLife.67379 |
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