Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages

Mitofusin 2 (MFN2) is a mitochondrial outer membrane GTPase, which modulates mitochondrial fusion and affects the interaction between endoplasmic reticulum and mitochondria. Here, we explored how MFN2 influences mitochondrial functions and inflammatory responses towards zymosan in primary human macr...

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Detalles Bibliográficos
Autores principales: Khodzhaeva, Vera, Schreiber, Yannick, Geisslinger, Gerd, Brandes, Ralf P., Brüne, Bernhard, Namgaladze, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397414/
https://www.ncbi.nlm.nih.gov/pubmed/34456930
http://dx.doi.org/10.3389/fimmu.2021.723683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397414/
https://www.ncbi.nlm.nih.gov/pubmed/34456930
http://dx.doi.org/10.3389/fimmu.2021.723683

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