Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches

A series of bis-thiazoles 5a–g were synthesized from bis-thiosemicarbazone 3 with hydrazonoyl chlorides 4a–g. Reaction of 3 with two equivalents of α-halocarbonyl compounds 6–8, 10, and 12a–d afforded the corresponding bis-thiazolidines 9, 11, and 13a–d, respectively. Condensation of bis-thiazolidin...

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Detalles Bibliográficos
Autores principales: Dawood, Kamal M., Raslan, Mohamed A., Abbas, Ashraf A., Mohamed, Belal E., Abdellattif, Magda H., Nafie, Mohamed S., Hassan, Mohamed K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397418/
https://www.ncbi.nlm.nih.gov/pubmed/34458233
http://dx.doi.org/10.3389/fchem.2021.694870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397418/
https://www.ncbi.nlm.nih.gov/pubmed/34458233
http://dx.doi.org/10.3389/fchem.2021.694870

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