Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP)

[Image: see text] This work describes the application of pentafluoropyridine (PFP), a cheap commercially available reagent, in the deoxyfluorination of carboxylic acids to acyl fluorides. The acyl fluorides can be formed from a range of acids under mild conditions. We also demonstrate that PFP can b...

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Detalles Bibliográficos
Autores principales: Brittain, William D. G., Cobb, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397423/
https://www.ncbi.nlm.nih.gov/pubmed/34251217
http://dx.doi.org/10.1021/acs.orglett.1c01953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397423/
https://www.ncbi.nlm.nih.gov/pubmed/34251217
http://dx.doi.org/10.1021/acs.orglett.1c01953

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