Cargando…

A Strategy to Conjugate Bioactive Fragments to Cytotoxic Diiron Bis(cyclopentadienyl) Complexes

[Image: see text] A series of bioactive molecules were synthesized from the condensation of aspirin or chlorambucil with terminal alkynes bearing alcohol or amine substituents. Insertion of the resulting alkynes into the iron–carbyne bond of readily accessible diiron bis(cyclopentadienyl) μ-aminocar...

Descripción completa

Detalles Bibliográficos
Autores principales: Schoch, Silvia, Hadiji, Mouna, Pereira, Sarah A. P., Saraiva, M. Lúcia M. F. S., Braccini, Simona, Chiellini, Federica, Biver, Tarita, Zacchini, Stefano, Pampaloni, Guido, Dyson, Paul J., Marchetti, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397425/
https://www.ncbi.nlm.nih.gov/pubmed/34475610
http://dx.doi.org/10.1021/acs.organomet.1c00270