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A Strategy to Conjugate Bioactive Fragments to Cytotoxic Diiron Bis(cyclopentadienyl) Complexes
[Image: see text] A series of bioactive molecules were synthesized from the condensation of aspirin or chlorambucil with terminal alkynes bearing alcohol or amine substituents. Insertion of the resulting alkynes into the iron–carbyne bond of readily accessible diiron bis(cyclopentadienyl) μ-aminocar...
Autores principales: | Schoch, Silvia, Hadiji, Mouna, Pereira, Sarah A. P., Saraiva, M. Lúcia M. F. S., Braccini, Simona, Chiellini, Federica, Biver, Tarita, Zacchini, Stefano, Pampaloni, Guido, Dyson, Paul J., Marchetti, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397425/ https://www.ncbi.nlm.nih.gov/pubmed/34475610 http://dx.doi.org/10.1021/acs.organomet.1c00270 |
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