Osimertinib Improves Overall Survival in Patients with Leptomeningeal Metastases Associated with EGFR-Mutated Non-Small-Cell Lung Cancer Regardless of Cerebrospinal Fluid T790M Mutational Status

Osimertinib has demonstrated promising efficacy against leptomeningeal metastasis (LM) associated with T790M-positive non-small-cell lung cancer (NSCLC). However, the effect of cerebrospinal fluid's (CSF's) epidermal growth factor receptor (EGFR) T790M mutation on osimertinib efficacy rema...

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Detalles Bibliográficos
Autores principales: Zhang, Milan, Ma, Weifeng, Liu, Huiqin, Jiang, Yushu, Qin, Lingzhi, Li, Wei, Zhang, Jiewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397557/
https://www.ncbi.nlm.nih.gov/pubmed/34457028
http://dx.doi.org/10.1155/2021/6968194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397557/
https://www.ncbi.nlm.nih.gov/pubmed/34457028
http://dx.doi.org/10.1155/2021/6968194

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