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Neurons expressing the aryl hydrocarbon receptor in the locus coeruleus and island of Calleja major are novel targets of dioxin in the mouse brain

The aryl hydrocarbon receptor (AhR) acts as a receptor that responds to ligands, including dioxin. The AhR–ligand complex translocates from the cytoplasm into the nucleus to induce gene expression. Because dioxin exposure impairs cognitive and neurobehavioral functions, AhR-expressing neurons need t...

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Detalles Bibliográficos
Autores principales: Kimura, Eiki, Kohda, Masanobu, Maekawa, Fumihiko, Fujii-Kuriyama, Yoshiaki, Tohyama, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397641/
https://www.ncbi.nlm.nih.gov/pubmed/33963922
http://dx.doi.org/10.1007/s00418-021-01990-1