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Inhibitors of PD-1/PD-L1 and ERK1/2 impede the proliferation of receptor positive and triple-negative breast cancer cell lines

PURPOSE: Triple-negative breast cancer (TNBC) is characterized by an unfavorable prognosis and missing systemic therapeutic approaches beside chemotherapy. Targeting the immune checkpoint PD-1/PD-L1 showed promising results in breast cancer and especially in TNBC. The extracellular signal-regulated...

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Detalles Bibliográficos
Autores principales: Bräutigam, Karen, Kabore-Wolff, Elodie, Hussain, Ahmad Fawzi, Polack, Stephan, Rody, Achim, Hanker, Lars, Köster, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397671/
https://www.ncbi.nlm.nih.gov/pubmed/34185141
http://dx.doi.org/10.1007/s00432-021-03694-4