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Design and synthesis of analogues of RA-VII—an antitumor bicyclic hexapeptide from Rubiae radix
The 14-membered cycloisodityrosine is the core structure of RA-series antitumor bicyclic peptides obtained from Rubia plants (Rubiaceae). In this study, an efficient method for the synthesis of cycloisodityrosines from commercially available l-tyrosine derivatives was developed. Using synthetic cycl...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Singapore
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397687/ https://www.ncbi.nlm.nih.gov/pubmed/34244894 http://dx.doi.org/10.1007/s11418-021-01542-w |