Cargando…
Selective involution of thymic medulla by cyclosporine A with a decrease of mature thymic epithelia, XCR1(+) dendritic cells, and epithelium-free areas containing Foxp3(+) thymic regulatory T cells
Immunosuppressive drugs such as cyclosporine A (CSA) can disrupt thymic structure and functions, ultimately inducing syngeneic/autologous graft-versus-host disease together with involuted medullas. To elucidate the effects of CSA on the thymus more precisely, we analyzed the effects of CSA on the th...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397693/ https://www.ncbi.nlm.nih.gov/pubmed/33993340 http://dx.doi.org/10.1007/s00418-021-01993-y |