HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer

In this study, two novel alternative splice variants of HER2, named HER2-PI9 and HER2-I12, were identified in breast cancer cell lines and breast tumour tissues. Whilst HER2-P19 arises from the inclusion of an 117 bp cassette-exon of intron 9 of HER2, HER2-I12 results from intron 12 inclusion. In si...

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Detalles Bibliográficos
Autores principales: Hart, Vic, Silipo, Marco, Satam, Swapna, Gautrey, Hannah, Kirby, John, Tyson-Capper, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397700/
https://www.ncbi.nlm.nih.gov/pubmed/34136934
http://dx.doi.org/10.1007/s00432-021-03689-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397700/
https://www.ncbi.nlm.nih.gov/pubmed/34136934
http://dx.doi.org/10.1007/s00432-021-03689-1

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