Whole exome and transcriptome sequencing reveal clonal evolution and exhibit immune-related features in metastatic colorectal tumors

Liver is the most common site where metastatic lesions of colorectal cancer (CRC) arise. Although researches have shown mutations in driver genes, copy number variations (CNV) and alterations in relevant signaling pathways promoted the tumor evolution and immune escape during colorectal liver metast...

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Detalles Bibliográficos
Autores principales: Li, Chunxue, Xu, Juan, Wang, Xiangfeng, Zhang, Chao, Yu, Zicheng, Liu, Jiucheng, Tai, Zaixian, Luo, Ziwen, Yi, Xin, Zhong, Zhaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397721/
https://www.ncbi.nlm.nih.gov/pubmed/34453042
http://dx.doi.org/10.1038/s41420-021-00607-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397721/
https://www.ncbi.nlm.nih.gov/pubmed/34453042
http://dx.doi.org/10.1038/s41420-021-00607-9

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