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Whole exome and transcriptome sequencing reveal clonal evolution and exhibit immune-related features in metastatic colorectal tumors
Liver is the most common site where metastatic lesions of colorectal cancer (CRC) arise. Although researches have shown mutations in driver genes, copy number variations (CNV) and alterations in relevant signaling pathways promoted the tumor evolution and immune escape during colorectal liver metast...
Autores principales: | Li, Chunxue, Xu, Juan, Wang, Xiangfeng, Zhang, Chao, Yu, Zicheng, Liu, Jiucheng, Tai, Zaixian, Luo, Ziwen, Yi, Xin, Zhong, Zhaoyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397721/ https://www.ncbi.nlm.nih.gov/pubmed/34453042 http://dx.doi.org/10.1038/s41420-021-00607-9 |
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