Development of multiplex digital PCR assays for the detection of PIK3CA mutations in the plasma of metastatic breast cancer patients

With the approval of new therapies targeting the PI3K pathway, the detection of PIK3CA mutations has become a key factor in treatment management for HR+/HER2− metastatic breast cancer (MBC). We developed multiplex digital PCR (dPCR) assays to detect and quantify PIK3CA mutations. A first screening a...

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Detalles Bibliográficos
Autores principales: Corné, Julien, Le Du, Fanny, Quillien, Véronique, Godey, Florence, Robert, Lucie, Bourien, Héloïse, Brunot, Angélique, Crouzet, Laurence, Perrin, Christophe, Lefeuvre-Plesse, Claudia, Diéras, Véronique, De la Motte Rouge, Thibault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397758/
https://www.ncbi.nlm.nih.gov/pubmed/34453076
http://dx.doi.org/10.1038/s41598-021-96644-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397758/
https://www.ncbi.nlm.nih.gov/pubmed/34453076
http://dx.doi.org/10.1038/s41598-021-96644-6

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