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SOX10 ablation severely impairs the generation of postmigratory neural crest from human pluripotent stem cells

Animal studies have indicated that SOX10 is one of the key transcription factors regulating the proliferation, migration and differentiation of multipotent neural crest (NC), and mutation of SOX10 in humans may lead to type 4 Waardenburg syndrome (WS). However, the exact role of SOX10 in human NC de...

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Detalles Bibliográficos
Autores principales: Lai, Xingqiang, Liu, Jia, Zou, Zhengwei, Wang, Yina, Wang, Ye, Liu, Xiao, Huang, Weijun, Ma, Yuanchen, Chen, Qian, Li, Fugui, Wu, Guifu, Li, Weiqiang, Wang, Weijia, Yuan, Yong, Jiang, Boxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397771/
https://www.ncbi.nlm.nih.gov/pubmed/34453037
http://dx.doi.org/10.1038/s41419-021-04099-4