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CTCF and transcription influence chromatin structure re-configuration after mitosis

During mitosis, transcription is globally attenuated and chromatin architecture is dramatically reconfigured. We exploited the M- to G1-phase progression to interrogate the contributions of the architectural factor CTCF and the process of transcription to genome re-sculpting in newborn nuclei. Deple...

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Detalles Bibliográficos
Autores principales: Zhang, Haoyue, Lam, Jessica, Zhang, Di, Lan, Yemin, Vermunt, Marit W., Keller, Cheryl A., Giardine, Belinda, Hardison, Ross C., Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397779/
https://www.ncbi.nlm.nih.gov/pubmed/34453048
http://dx.doi.org/10.1038/s41467-021-25418-5