Cargando…
CTCF and transcription influence chromatin structure re-configuration after mitosis
During mitosis, transcription is globally attenuated and chromatin architecture is dramatically reconfigured. We exploited the M- to G1-phase progression to interrogate the contributions of the architectural factor CTCF and the process of transcription to genome re-sculpting in newborn nuclei. Deple...
Autores principales: | Zhang, Haoyue, Lam, Jessica, Zhang, Di, Lan, Yemin, Vermunt, Marit W., Keller, Cheryl A., Giardine, Belinda, Hardison, Ross C., Blobel, Gerd A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397779/ https://www.ncbi.nlm.nih.gov/pubmed/34453048 http://dx.doi.org/10.1038/s41467-021-25418-5 |
Ejemplares similares
-
Chromatin Structure Dynamics During the Mitosis to G1-Phase Transition
por: Zhang, Haoyue, et al.
Publicado: (2019) -
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
por: Luan, Jing, et al.
Publicado: (2021) -
Genome accessibility is widely preserved and locally modulated during mitosis
por: Hsiung, Chris C.-S., et al.
Publicado: (2015) -
Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility
por: Behera, Vivek, et al.
Publicado: (2018) -
A hyperactive transcriptional state marks genome reactivation at the mitosis–G1 transition
por: Hsiung, Chris C.-S., et al.
Publicado: (2016)