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Enhancement of bioactivity, thermal stability and tumor retention by self-fused concatenation of green fluorescent protein

The widespread application of protein and peptide therapeutics is hampered by their poor stability, strong immunogenicity and short half-life. However, the existing protein modification technologies require the introduction of exogenous macromolecules, resulting in inevitable immunogenicity and decr...

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Detalles Bibliográficos
Autores principales: Hu, Jin, Shi, Jianquan, Yuan, Yeshuang, Zhang, Bo, Li, Shengjie, Dong, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397794/
https://www.ncbi.nlm.nih.gov/pubmed/34485712
http://dx.doi.org/10.1016/j.bbrep.2021.101112