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Enhancement of bioactivity, thermal stability and tumor retention by self-fused concatenation of green fluorescent protein
The widespread application of protein and peptide therapeutics is hampered by their poor stability, strong immunogenicity and short half-life. However, the existing protein modification technologies require the introduction of exogenous macromolecules, resulting in inevitable immunogenicity and decr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397794/ https://www.ncbi.nlm.nih.gov/pubmed/34485712 http://dx.doi.org/10.1016/j.bbrep.2021.101112 |