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EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop

Rapid tumor progression, metastasis, and diagnosis in advanced stages of disease are the main reasons for the short survival time and high mortality rate of patients with hepatocellular carcinoma (HCC). Ephrin A4 (EFNA4), the ligand of the EPH family, participates in the development of blood vessels...

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Detalles Bibliográficos
Autores principales: Lin, Junhao, Zeng, Chunting, Zhang, JiaKang, Song, Zhenghui, Qi, Na, Liu, Xinhui, Zhang, Ziyan, Li, Aimin, Chen, Fengsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397841/
https://www.ncbi.nlm.nih.gov/pubmed/34484860
http://dx.doi.org/10.1016/j.omtn.2021.06.002