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EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop
Rapid tumor progression, metastasis, and diagnosis in advanced stages of disease are the main reasons for the short survival time and high mortality rate of patients with hepatocellular carcinoma (HCC). Ephrin A4 (EFNA4), the ligand of the EPH family, participates in the development of blood vessels...
Autores principales: | Lin, Junhao, Zeng, Chunting, Zhang, JiaKang, Song, Zhenghui, Qi, Na, Liu, Xinhui, Zhang, Ziyan, Li, Aimin, Chen, Fengsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397841/ https://www.ncbi.nlm.nih.gov/pubmed/34484860 http://dx.doi.org/10.1016/j.omtn.2021.06.002 |
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