AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth

Peroxisome proliferator–activated receptor δ (PPARδ) is a nuclear receptor transcription factor that plays an important role in the regulation of metabolism, inflammation, and cancer. In addition, the nutrient-sensing kinase 5′AMP-activated protein kinase (AMPK) is a critical regulator of cellular e...

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Detalles Bibliográficos
Autores principales: Ding, Jiajun, Gou, Qian, Jia, Xiao, Liu, Qian, Jin, Jianhua, Shi, Juanjuan, Hou, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397901/
https://www.ncbi.nlm.nih.gov/pubmed/34270958
http://dx.doi.org/10.1016/j.jbc.2021.100954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397901/
https://www.ncbi.nlm.nih.gov/pubmed/34270958
http://dx.doi.org/10.1016/j.jbc.2021.100954

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