External Evaluation of Population Pharmacokinetic Models and Bayes-Based Dosing of Infliximab

Despite the well-demonstrated efficacy of infliximab in inflammatory diseases, treatment failure remains frequent. Dose adjustment using Bayesian methods has shown in silico its interest in achieving target plasma concentrations. However, most of the published models have not been fully validated in...

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Detalles Bibliográficos
Autores principales: Konecki, Celine, Feliu, Catherine, Cazaubon, Yoann, Giusti, Delphine, Tonye-Libyh, Marcelle, Brixi, Hedia, Cadiot, Guillaume, Biron, Amélie, Djerada, Zoubir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398005/
https://www.ncbi.nlm.nih.gov/pubmed/34452152
http://dx.doi.org/10.3390/pharmaceutics13081191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398005/
https://www.ncbi.nlm.nih.gov/pubmed/34452152
http://dx.doi.org/10.3390/pharmaceutics13081191

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